On the system settings page (/admin/setup), I think it would be nice to see sections put together where products, addons, domain pricing, etc are all grouped together and then have a few other groups to sort of break things up and make it easier for admins to quickly find the settings they are looking for. Right now, it's kind of a pain to read through option after option with no real organization to it.
Possible sections could be:
Products / Services (to include products, product addons, domain pricing, product bundles, configurable options)
Modules (to include payment gateways, domain registrars, addon modules, servers)
Then a couple of other groups as you see fit.